SP-0233 Optimal use of inverse optimization in brachytherapy
نویسندگان
چکیده
منابع مشابه
Linear Conic Optimization for Inverse Optimal Control
We address the inverse problem of Lagrangian identification based on trajectories in the context of nonlinear optimal control. We propose a general formulation of the inverse problem based on occupation measures and complementarity in linear programming. The use of occupation measures in this context offers several advantages from the theoretical, numerical and statistical points of view. We pr...
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15 صفحه اولSU-E-T-430: Evaluation of Inverse Optimization in Brachytherapy for Locally Advanced Cervix Cancer.
PURPOSE Brachytherapy is a vital part of treating locally advanced cervix cancer. Point-based 2D treatment planning is conventionally used. New CT/MRI-compatible applicators for HDR brachytherapy make 3D conformal planning possible. GEC-ESTRO endorsed the EMBRACE (intErnational study on MRI-guided BRachytherapy in locally Advanced CErvical cancer) protocol which recommends standard-plan-based m...
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Current inverse treatment planning methods that optimize both catheter positions and dwell times in prostate HDR brachytherapy use surrogate linear or quadratic objective functions that have no direct interpretation in terms of dose-volume histogram (DVH) criteria, do not result in an optimum or have long solution times. We decrease the solution time of the existing linear and quadratic dose-ba...
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Publications have reported the benefits of using high-dose-rate brachytherapy (HDRB) for the treatment of prostate cancer, since it provides similar biochemical control as other treatments while showing lowest long-term complications to the organs at risk (OAR). With the inclusion of anatomy-based inverse planning opti- mizers, HDRB has the advantage of potentially allowing dose escalation. Amo...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2019
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(19)30653-x